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Diversification of binding in ribose-binding protein
(RBP). RBP has been modified to bind to a number of different target
molecules.
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BIOINFORMATICS
The
urgency of anticipating and preparing for terrorist attacks became
obvious on September 11, 2001. In response to the need for fast,
accurate real-time detection and identification of emerging chemical
and biological agents, the Department of Homeland Security (DHS) began
funding the development of new technologies in this area.
The
Information Sciences Division received DHS funding for a collaborative
project with Professor Andrew Ellington of the University’s Department
of Chemistry and Biochemistry (see http://www.ellingtonlab.org).
The objective of this project is to develop a process that will create
sensors/receptors within two weeks from the time a new threat is
identified. To this end, ISD
has developed a secure computing facility with a Beowulf cluster and
Biosafety
Level 2 lab, and is pursuing the computational design, fabrication, and
testing of receptors for a number of targets.
For further information regarding
SPD's work in bioinformatics, please contact:
Director-SISL@arlut.utexas.edu
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